Installed package content got corrupted in some situations like
with /gnu/ on lvm disk when disk full which later resized online with lvresize

$ df /gnu

Filesystem                        Size  Used Avail Use% Mounted on
/dev/mapper/VGguix-gnu  116G  115G  0G  100% /gnu

which later fixed by below command online, while guix upgrade/install is going

$ LVPART=/dev/mapper/VGguix-gnu

$ sudo fsck -n $LVPART

$ sudo lvresize -L +10G $LVPART

$ sudo resize2fs $LVPART

$ sudo fsck -n $LVPART

For example

/gnu/store/lysmrhh9i44aawwx406829lw581jizq6-qtbase-5.15.15/lib/libQt5Concurrent.so.5.15.15

file content become zero as during installation space become full due to less disk space space.

and
sudo guix gc  --verify=repair,contents

also not fixed these issues

and when I has reinstalled whole guixsd os again things started working

Similar case now happened for

/gnu/store/i7z4r54cic4g5s15b1q9k1w5a6kvwadw-gvfs-1.56.1/lib/gvfs/libgvfscommon.so

$ md5sum /gnu/store/i7z4r54cic4g5s15b1q9k1w5a6kvwadw-gvfs-1.56.1/lib/gvfs/libgvfscommon.so
9543d63a0c2bf7396bd138e0ceb090fa  /gnu/store/i7z4r54cic4g5s15b1q9k1w5a6kvwadw-gvfs-1.56.1/lib/gvfs/libgvfscommon.so

And here is not way to reinstall it as many other packages are depending on it

$ guix gc -D  /gnu/store/i7z4r54cic4g5s15b1q9k1w5a6kvwadw-gvfs-1.56.1                    
finding garbage collector roots...                        
guix gc: error: cannot delete path `/gnu/store/i7z4r54cic4g5s15b1q9k1w5a6kvwadw-gvfs-1.56.1' since it is still alive

This force me to reinstall whole GuixSD

So the grantee that package content will be same is broken in case of disk full error ( followed by  recover by increasing space online.)

* Either this should not happen at first place, if content error happen then abort install operation

 (means after install ensure if install is really as expected.)

* Or here were some kind of repair-ability to get out of this problem as

   $ sudo guix gc  --verify=repair,contents

 also not help here

Regards and Thanks,
--

/shyam