On Gnome 46 / Wayland with the Guix system (and linux kernel 6.13) and a 200% scaled display, some applications are not scaled correctly, e.g. gimp, vorta, vlc, freecad.
Default gnome desktop applications, as well as other non-gnome applications (libreoffice, icecat, etc.) are correctly scaled.

These applications (gimp, vorta, vlc, freecad) were correctly scaled on Gnome 44.

The problem appeared after a guix pull from gnome 44 to gnome 46 but the problem can be reproduced from a fresh installation of guix system with the gnome 46 desktop.

I'll be happy to give you more details if necessary.

Christophe