I've added file-remote-p guards in a variety of places specifically to avoid these issues. 

On Wed, Oct 9, 2024 at 9:39 AM Dmitry Gutov <dgutov@yandex.ru> wrote:
Hi!

On 09/10/2024 13:43, Ergus via Bug reports for GNU Emacs, the Swiss army
knife of text editors wrote:
> I made a profile and it looks like there is some bad interaction between
> project-mode-line and tramp names
>
> I already tried:
>
> (connection-local-set-profile-variables 'my-profile '((project-mode-line . nil)))
> (connection-local-set-profiles '(:application tramp :user "myuser") 'my-profile)
>
> But is not disabling the modeline for remote files.

I wonder if we'll need to disable project-mode-line in remote files
altogether, or if this is a problem that could be solved in Tramp (with
extra caching?)

To use connect-local value to disable, BTW, it would need to have extra
code called from the mode line format (in bindings.el). And it's a part
that was added only recently, for in Emacs 30.