Hi, It looks like Numba is CPU specific as I could build it all the time on AMD Ryzen 7 3800X 8-Core Processor, but it fails to pass tests on ci.guix.gnu.org on other user's machines. It supports Pytest as test runner (PR #4781: WIP/runtest cf pytest)[1] I might refactor the package to skip tests in #:tests-flags instead altering tests files. Meanwhile reviewing patch and build python-numba after apply. 1. https://github.com/numba/numba/blob/05b4cad9e10132c6c0166e76d80b034a18bce33a/docs/source/release-notes.rst#L3198 -- Oleg