Tested under Emacs 28.1 and a recent tip of the Emacs git repo for Emacs
29 with asynchronous native compilation enabled:

M-x package-install RET hyperbole RET

fails to load the hyperbole-autoloads.el file before the
async native compiler and byte compiler produce these errors since
the autoloaded var:append function is not defined:

Warning (comp): ~/.emacs.d/elpa/hyperbole-8.0.0/hui-em-but.el: Error:
Symbol's function definition is void var:append Disable showing Disable
logging
Warning (comp): ~/.emacs.d/elpa/hyperbole-8.0.0/hui-mouse.el: Error:
Symbol's function definition is void var:append Disable showing Disable
logging
Warning (comp): ~/.emacs.d/elpa/hyperbole-8.0.0/hbut.el: Error: Symbol's
function definition is void var:append Disable showing Disable logging

The package manager definitely generates hyperbole-autoloads.el at some
point though I do not know if it is before these errors are produced.

Thanks for any help with this.

-- Bob