Your bug report #42259: emacs-ess 18.10.2 sets R_HOME to a ridiculous value by default which was filed against the guix package, has been closed. The explanation is attached below, along with your original report. If you require more details, please reply to 42259@debbugs.gnu.org. -- 42259: http://debbugs.gnu.org/cgi/bugreport.cgi?bug=42259 GNU Bug Tracking System Contact help-debbugs@gnu.org with problems